Endocrine Abstracts

Background: Glucose metabolism derangements (GMD) and thyroid nodules (TN) are the most frequent endocrine disorders. A relationship between these conditions has been suggested, but data are still controversial and no evidence was reported regarding sex differences.Aim: To evaluate the distribution of impaired fasting glucose (IFG), normal glucose tolerance (NGT), impaired glucose tolerance (IGT), type 2 diabetes (T2DM) and TN according to sex.<p cla...

Introduction: Patients with transfusion-dependent β-thalassemia (TDT) frequently exhibit elevated urinary calcium excretion, contributing to kidney stone formation and osteoporosis. The underlying mechanism of hypercalciuria in β-thalassemia remains elusive, with FGF23 playing a potential role. FGF23, a bone-derived hormone, primarily acts on the kidneys by inhibiting phosphate reabsorption in the proximal tubules while enhancing calcium uptake in the distal tubules....

Background: Patients with transfusion-dependent β -thalassemia (TDT) often experience several endocrine complications, including diabetes mellitus (DM). In TDT, the reliability of glycated haemoglobin (HbA1c) assessment is compromised due to elevated erythrocytes turnover and frequent transfusions. Glycated Albumin (GA), a product of non-enzymatic albumin glycation, has been investigated as a medium-term glycaemic marker (21 days) in the general diabetic population. Since...